Characterization of Ex Vivo Nonmelanoma Skin Tissue Using Raman Spectroscopy

High Performance Method for Skin Roughness Detection Using Raman Spectroscopy

high performance method for skin roughness detection using raman spectroscopy

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Detection and Characterization of Human Teeth Caries Using 2D Correlation Raman Spectroscopy

Background: Carious lesions are formed by a complex process of chemical interaction between dental enamel and its environment. They can cause cavities and pain, and are expensive to fix. It is hard to characterize in vivo as a result of environment factors and remineralization by ions in the oral cavity. Objectives: The development of a technique that gives early diagnosis which is non-invasi...

Raman spectroscopic analysis of human skin tissue sections ex-vivo: evaluation of the effects of tissue processing and dewaxing.

Raman spectroscopy coupled with K-means clustering analysis (KMCA) is employed to elucidate the biochemical structure of human skin tissue sections and the effects of tissue processing. Both hand and thigh sections of human cadavers were analyzed in their unprocessed and formalin-fixed, paraffin-processed (FFPP), and subsequently dewaxed forms. In unprocessed sections, KMCA reveals clear differ...

Imaging of ex vivo nonmelanoma skin cancers in the optical and terahertz spectral regions

With approximately 3.5 million cases diagnosed each year, nonmelanoma skin cancer (NMSC) is the most common form of cancer. NMSC results in about 3000 deaths each year and the cost of treatments is estimated to exceed $ 600 million each year [1]. The most effective form of NMSC treatment is Mohs Micrographic Surgery (MMS) which involves removing cancer layer by layer while simultaneously proces...